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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1454 | Acyclovir | Aciclovir,Acycloguanosine | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , HSV |
Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus fam... | |||
T19101 | 2'-Fluorothymidine | 2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine | Others |
2'-Fluorothymidine(2'-Deoxy-2'-fluoro-5-Methyluridine) belongs to the thymidine (TdR) and methyluridine isozymes and is a highly selective substrate for thymidine kinase type 2 (TK2). | |||
T20436 | DHQ | 2,3-dihydroxy-quinoxalin | ATPase |
DHQ (2,3-dihydroxy-quinoxalin) is an inducer of ATPase activity that of Herpes Simplex Virus thymidine kinase. | |||
T1643 | Penciclovir | BRL 39123,VSA 671 | HCV Protease , Antifection , HSV |
Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kinase and subsequently converted by cellular kinases into the ... | |||
T71475 | Bucyclovir triphosphate | ||
Bucyclovir triphosphate is an antiherpes and cyclic guanosine analog activated by the viral thymidine kinase to inhibit viral DNA synthesis in infected cells. | |||
T83821 | Thymidine-5'-O-(α,β-methylene)diphosphate sodium | α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP | |
Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deo... | |||
T73980 | Thymidine 5′-diphosphate | ||
Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), requiring ATP ... | |||
T68917 | Fazarabine | ||
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is ph... | |||
T80655 | BVDU 5′-Triphosphate | BVdUTP,(E)-5-(2-Bromovinyl)-dUTP | DNA/RNA Synthesis |
BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase. It exhibits outstanding selectivity for varicella-zoster virus (VZV) and herpes simplex virus type 1... | |||
T68631 | Carbetimer | ||
Carbetimer is a partially imidized copolymer of ethylene & maleic anhydride with average MW approx 1,200 daltons; capable of specific stimulation of immune response. Carbetimer is a low molecular weight polymer derived f... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01386 | TK1 Potein, Canine, Recombinant (His) | Canine | E. coli |
Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phas... | |||
TMPJ-00769 | TK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identifi... | |||
TMPJ-00905 | DTYMK Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolis... | |||
TMPY-04542 | CDK2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinas... |